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Facoltā di Scienze Agrarie e Alimentari Universitā degli Studi di Milano
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Ecology of human microbiota
Code: K050NB
Teacher:  Simone Domenico Guglielmetti
Year: 
Term: 
CFU:  2,5 
CFU subdivision: Lectures: 2,5
Basic aims:  Info not available
Acquired skills:  Info not available
Course contents:  The main functions of the human intestinal microbiota. The
dependence of the gut microbiota on diet carbohydrates. The co-
evolution between intestinal microorganisms and the host. The
effect of diet on intestinal microbiota. The effect of antibiotics on
the intestinal microbiota. The intestinal appendix and the gut
microbiota. The fecal microbiota transplant. The harmful activities
of intestinal microbiota. The immune system and commensal
microorganisms. Relationship between diet, gut microbiota &
human health. The microbiota-gut-brain axis.
Program:  The main functions of the human intestinal microbiota.
The intestine as bioreactor for carbohydrates.
The dependence of the gut microbiota on diet carbohydrates.
The co-evolution between intestinal microorganisms and the host.
The effect of diet on intestinal microbiota: the case of Italian vs Burkina Faso children; intestinal microbiota and obesity.
The effect of antibiotics on the intestinal microbiota: consequences of antibiotic consumption in infancy.
Breast milk and bifidobacteria.
The potential role of the intestinal appendix in maintaining intestinal microbiota structure and intestinal health.
The fecal microbiota transplant. The harmful activities of intestinal microbiota.
The immune system: basics and interaction with commensal microorganisms.
Relationship between diet, gut microbiota & human health: analysis of 6 case studies
([i] high-fat diet and liver cancer,
[ii] sodium chloride and hypertension,
[iii] dietary fiber and protection from intestinal polyps;
[iv] carnitine/choline and atherosclerosis;
[v] artificial sweeteners and glucose intolerance;
[vi] milk fats and intestinal inflammation).
The microbiota-gut-brain axis.
Prerequisites:  Basic knowledge of microbiology and biochemistry.
Preparatory instructions:  None
Learning materials:  Presentations shown in class available in PDF format on the Ariel
platform.
Other info:  The exam is organized in a written test consisting of open
questions, with a maximum value of 30/30 and honors. Any
additional information on the exam will be illustrated during the
course.
DOWNLOAD
Program of Ecology of human microbiota (pdf version)
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