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Facoltā di Scienze Agrarie e Alimentari Universitā degli Studi di Milano
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Biodiversity and biotechnologies in animal husbandry
Code: G610E-
Teacher:  Paola Crepaldi
CFU subdivision: Lectures: 5
Practices in classroom: 1
Basic aims:  The course offers an outline of the principal biotechnologies applied to the characterisation of species, breeds and animal products. Issues and expectations concerning genetic variability, strategy for gene discovery, biotechnologies of reproduction and animal transgenesis will be discussed.
Acquired skills:  Knowledge of genetic improvement of animal products issues with traditional and biotechnological tools. Skills in processing and interpreting main themes concerning protection of genetic variability in domestic animals. Expertise in present applications of molecular biotechnology and future prospects in the field of animal husbandry.
Course contents:  Breeds and species in animal husbandry. Role and classical tools of genetic improvement of quanti-qualitative traits of animal products. Present of molecular biothcnologies and future prospects in animal husbandry: gene and marker assisted selection, reproductive biotechnologies and transgenesis. Biodiversity: organization levels and measures. Analyses of genetic variability in farm animal species.
Program:  Breeds and species in animal husbandry. Animal products.Introduction and history of genetic breeding in animals husbandry. The products of farm animals.Principal dairy species and breeds.Principal meat species and breeds.Role and tools of classical genetic breeding to improve quanti-qualitative traits of animal production. Limits of selection and breeding. Role and perspectives of molecular biotechnologies in animals. Farm animal genomes: sequencing projects, genomic annotation, bioinformatic tools. Comparative genomics applied to farm animal studies.Search for genes associated to production traits: the candidate gene approach. Gene assisted selection: examples of polymorphisms in candidate genes involved in quanti-qualitative productions of farm animals. Marker assisted selection. Microsatellites and paternity test. QTLs search and applications to animal products improvements. Single Nucleotide Polymorphisms (SNPs) and their utility in animal husbandry. Molecular markers and animal products traceability (at animal, breed and species level).Biodiversity: organisation levels of biodiversity and measures. Genetic diversity and measures. Management of intraspecific genetic diversity, candidate species to domestication and domestic species. Molecular knowledge applied to the history of domestication of principal farm animals. Biotechnology of reproduction and transgenic animals: artificial insemination, embryo transfer and MOET schemes, ovum pick up, semen and embryo sexing. Cloning techniques, perspectives of cloned animals in animal husbandry. Transgenic animals: traits of interest, applications and perspectives.
Prerequisites:  Scientific knowledge of genetics, biology, molecular biology and basic statistical analyses of field data.
Preparatory instructions:  Genetics, biology, molecular biology
Learning materials:  Course notes Scientific papers. Attending student will be directly supplied with teaching aids.
Other info:  The course consists of frontal lessons and classroom practice.
The exam consists of an oral interview designed to assess the knowledge of the course topics. The scoring is based on analysis, connection and application skills of the course issues and on the use of the technical language of the subject.
Program of Biodiversity and biotechnologies in animal husbandry (pdf version)
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